FIGURE 8.

C-A1 is influenced by cypA. A, SupT1 cells infected with a VSV-G pseudotyped HIV-1 vector at an m.o.i. of 0.05 in the presence of 4 μm C-A1 or 2 μm CsA; drugs were added at the indicated time post-infection and cells analyzed by FACS 2 weeks post-infection. Data are representative of two independent experiments. B, SupT1 cells were infected with a HIV-1 vector at an m.o.i. of 0.05 in the presence of the indicated concentration of CsA with or without a fixed concentration of C-A1 (2 μm) and analyzed by FACS 2 weeks post-infection. Data are representative of four experiments. C, SupT1 cells were infected at with wild type or a P90A mutant HIV-1 vector at an m.o.i. 0.8 in the presence of the indicated concentrations of C-A1. Samples were analyzed by FACS 2 weeks post-infection. Data are representative of four experiments.