FIGURE 3.

Comparison between the inhibitor complex and the apo form. Both forms are the wild-type enzymes. A, the environment around the active site. The complex with 2-CABP and the apo form (PDB code 1GEH) are shown in green and yellow, respectively. A 2-CABP molecule is shown as a stick model, and hydrogen bonds are indicated by blue dashed lines. The movement of the C-terminal loop is indicated by a red arrow. B, the molecule opposite (A) in the functional dimer. The complex with 2-CABP and the apo form are shown in dark and light blues, respectively. The movements of the loops are indicated by red arrows, and the N-terminal region, which cannot be observed in the apo form, is indicated by a red dashed circle.