Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Heme responsiveness in the hrg-1 promoter is mediated by a 15-bp region containing an E-box. A, schematics for the synthesis of mut1 to mut5 by mutating five consecutive nucleotides at a time within the 23-bp HERE. Double-headed arrows indicate the location of inverse repeats. B, GFP was quantified in C. elegans transformed with mut1, mut2, mut3, mut4, or mut5 and supplemented with 2 or 40 μm heme. The y axis is the GFP level in arbitrary units. ***, p < 0.001.
