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ELT-2 and ELT-4 are essential for the heme regulation of hrg-1. A, synchronized IQ6011 L3 larvae were fed HT115(DE3) bacteria grown in 4 μm heme and induced to produce double-stranded RNA against elt-1, elt-2, elt-4, elt-6, or elt-7, and GFP was analyzed by microscopy. B, quantification of the GFP expression in A. The y axis is the GFP level in arbitrary units. ***, p < 0.001.
