FIGURE 3.

Molecular functions of SRC-3. Presented is a schematic representation of how PTMs selectively code the numerous molecular functions of SRC-3, which include, but are not limited to, amplification of steroid- and mitogen-mediated gene transcription, regulation of RNA splicing, translational corepression, modulation of energy homeostasis, and control of cellular motility. TNFR, TNF receptor; EGFR, EGF receptor; FAK, focal adhesion kinase; CoCoA, co-coactivator; Ub, ubiquitin; TBP, TATA-binding protein; TAFIIs, TATA-binding protein-associated factors; Pol II, RNA polymerase II; PPTases, phosphatases; GTF, general transcription factor.