TABLE 2.

Molecular chaperones whose stress-induced expression was affected by deletion of OGT

Complete data are shown under supplemental Table 2. -Fold change as compared to control is reported at each time point.

Protein	OGT wild-type			OGT null
	0.5 h at 45 °C	1 h at 45 °C	1 h at 45 °C, 0.5 h at 37 °C	0.5 h at 45 °C	1 h at 45 °C	1 h at 45 °C, 0.5 h at 37 °C
Proteins up-regulated in OGT null cells
Dnajb8	0.58	1.16	1.18	1.17a	2.46	5.54
Dnajc5b	0.88	1.18	0.87	0.97	1.26	1.62
Dnajc5g	2.52	29.83	32.45	6.64	39.84	73.20b
Proteins down-regulated in OGT null cells
Bag2	1.52	1.52	1.56	1.08c	0.98c	1.12b
Bag3	2.59	3.85	7.97	1.94	2.44b	3.68b
Cct4	1.56	2.07	1.50	0.94	0.99b	0.86a
Cryab	1.22	1.33	1.43	0.98a	0.95	1.01b
Dnaja1	2.17	2.02	2.81	1.34	1.61	1.88c
Dnaja2	1.18	1.28	1.33	0.88c	0.78	0.97b
Dnaja3	1.25	1.36	1.22	0.88b	0.86a	0.92c
Dnaja4	4.56	6.81	36.60	3.85	6.18	16.63
Dnajb1	7.31	11.91	27.03	6.67	9.31	16.09b
Dnajb7	3.49	5.63	4.78	2.32c	3.37b	3.03
Hsph1	3.81	6.28	7.00	1.86	2.96	3.76
Hsp90aa1	1.40	2.23	2.28	1.11c	1.36	1.79c
Hspa1ad	87.48	270.16	1101.90	43.39	139.06a	513.61b
Hspa1bd	49.26	179.84	368.97	43.26	107.72c	248.50a
Hspb1	7.30	15.73	22	4.29c	7.91	11.18b
Hspb8	1.55	1.99	2.75	1.26c	1.54c	1.81c
Hspd1	1.77	1.87	1.98	0.92	1.10	1.19a
	1.51	2.27	3.04	1.56	1.51	1.91

^a p value <0.01. p values derived from t test comparing chaperone expression in wild-type and OGT null cells are each time point.

^b p value <0.05 derived from t test comparing chaperone expression in wild-type and OGT null cells are each time point.

^c p value <0.1 derived from t test comparing chaperone expression in wild-type and OGT null cells are each time point.

^d The proteins transcribed from these genes are known as HSP72.