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Whole-body SPECT/CT images of B16/F1 flank melanoma-bearing C57 mice at 2 (A) and 24 h (B) post-injection of 37 MBq (1 mCi) of 111In-DOTA-Nle-CycMSHhex. Tumor (T) and kidneys (K) are highlighted with arrows on the images. HPLC profile (C) of radioactive urine sample of a B16/F1 melanoma-bearing C57 mouse at 2 h post-injection of 111In-DOTA-Nle-CycMSHhex. 111In-DOTA-Nle-CycMSHhex remained intact in the urine 2 h post-injection.
