Figure 6.

Control of granular layer spatio-temporal dynamics by Golgi cell inhibition A, stimulation of a mossy fibre beam elicits local field potentials in the granular layer, which can be composed by more spikes generated in sequence by granule cells. Activation of the feed-forward inhibitory Golgi cell loop limits spike emission (time-window effect; from Mapelli & D’Angelo, 2007). B, stimulation of a mossy fibre beam elicits local field potentials in the granular layer, which are surrounded by lateral inhibition generated by Golgi cells (centre–surround effect; from Mapelli & D’Angelo, 2007).