Figure 5. PKC activation with PMA affects state time constants and distribution of open and closed states.

A, mean open state time constant ±s.e.m. in response to 0.1 μm capsaicin, and 0.1 μm capsaicin in the presence of PMA. B, mean percentage contribution of each open state to total open time. C and D, similar graphs for closed states. Significance levels: **P < 0.01, ***P < 0.001 with respect to values in absence of PMA.