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Modulation of TRPV1 S502A/S801A activity by PMA (A, 0.1 μm) and staurosporine (B, 0.2 μm). C, mean amplitude ±s.e.m. and average open probability (Popen) ±s.e.m. for S502A/S801A activity in response to 0.1 and 0.25 μm capsaicin. Significance ***P < 0.001.
