Table 2. Biokinetic rates derived previously from three independent cartilage engineering experiments each having unique biochemical modulation results [29,30].
Scaffold | Cell type | Ref. | GAGss | τGAG (days) | Collagenss | τcollagen (days) | Rates: growth (λ) and decay (δ) | |
---|---|---|---|---|---|---|---|---|
λGAG | λcollagen | |||||||
δGAG | δcollagen | |||||||
PGA | BAC | 37 | 6.8% ww | 31.3 | 3.7% ww | 15.9 | 3.256×10−2 | 6.672×10−2 |
6.139×10−4 | 3.837×10−3 | |||||||
PGA | BAC | 36 | 6.1% dw | 187.0 | 6.5% dw | 18.9 | 5.474×10−3 | 5.400×10−2 |
1.264×10−4 | 1.108×10−3 | |||||||
PGA | BAC | 38 | 1.6% ww | 22.2 | 2.4% ww | 16.7 | 5.900×10−2 | 6.800×10−2 |
1.400×10−2 | 8.363×10−3 |
PGA=polyglycolic acid.
BAC=bovine articular cartilage.
ww, dw=wet weight, dry weight.