TABLE 1.
Frequency of fixation and fitness of beneficial mutations
| Frequency of fixation (%) |
Relative fitness |
|||||
|---|---|---|---|---|---|---|
| Beneficial mutation | A455G | A455T | C1550T | A455G | A455T | C1550T |
| 1630+CCCGTG | 0 | 0 | 1.28 | 1.43 | ||
| A1540C | 0 | 0 | 1.28 | 1.40 | ||
| A1553G | 0 | 1.28 | 3.85 | 1.68 | 1.69 | |
| A1553T | 0 | 0 | 3.85 | 1.64 | ||
| A1562G | 20 | 19.23 | 7.69 | 1.75 | 1.65 | 1.51 |
| A1562T | 1.43 | 0 | 0 | 1.92 | ||
| A1567G | 0 | 2.56 | 0 | 1.94 | ||
| A1592T | 0 | 1.28 | 0 | 1.78 | ||
| A1718G | 0 | 1.28 | 0 | 1.24 | ||
| A1729C | 1.43 | 0 | 0 | 1.89 | ||
| A455G | NP | NP | 5.26 | NP | NP | 1.63 |
| A455T | NP | NP | 47.37 | NP | NP | 1.63 |
| C1341A | 0 | 0 | 1.28 | 1.74 | ||
| C1375T | 0 | 0 | 1.28 | 1.63 | ||
| C1547T | 1.43 | 0 | 0 | 1.45 | ||
| C1550G | 0 | 1.28 | 0 | 1.70 | ||
| C1550T | 7.14 | 11.54 | NP | 1.86 | 1.52 | NP |
| C1563A | 1.43 | 0 | 0 | 1.67 | ||
| C1563G | 0 | 1.28 | 1.28 | 1.49 | 1.56 | |
| C1591G | 2.86 | 0 | 1.28 | 1.91 | 1.67 | |
| C1591T | 0 | 5.13 | 1.28 | 1.48 | 1.66 | |
| C1593A | 1.43 | 0 | 0 | 1.82 | ||
| C1607T | 0 | 1.28 | 1.28 | 1.39 | 1.25 | |
| C1610T | 0 | 0 | 1.28 | 1.40 | ||
| C1619T | 0 | 0 | 1.28 | 1.18 | ||
| C1736T | 2.86 | 1.28 | 1.28 | 1.76 | 1.84 | 1.39 |
| G1561A | 0 | 0 | 1.28 | 1.51 | ||
| G1622A | 0 | 0 | 1.28 | 1.65 | ||
| G1624T | 0 | 0 | 1.28 | 1.54 | ||
| G1716T | 0 | 0 | 1.28 | 1.58 | ||
| G1724C | 1.43 | 0 | 0 | 1.45 | ||
| T1529C | 1.43 | 0 | 0 | 1.44 | ||
| T1549G | 2.86 | 1.28 | 0 | 1.96 | 1.20 | |
| T1655G | 0 | 0 | 1.28 | 1.39 | ||
| T1731C | 0 | 1.28 | 0 | 1.12 | ||
| T449C | 7.69 | 5.26 | 0 | 1.73 | 1.31 | |
| Sum | 53.42 | 55.24 | 88.5 | |||
This table shows the frequency of fixation and the relative fitness of beneficial mutations identified in this study across all three genetic backgrounds used to initiate selection lines. NP indicates mutations that were not physically possible.