Figure 4. Lifespans of wild-type animals and mutants treated with 0.1 mM paraquat (PQ).
The treatment had a dramatic lifespan-lengthening effect on the wild type (A) but no effect on the nuo-6 (B) and isp-1 (C) respiratory chain subunit mutants. In contrast, the treatment had a dramatic additive effect on the long-lived clk-1 (D) and eat-2 (E) mutants. The treatment has only a very moderate effect on daf-2 mutants (F) but a strong effect on sod-2 mutants (G). See Tables 1 and S1 for details of genotype, sample size, and statistical analysis.