Table 1.
Characteristics of study populations.
| DRUID | AUSDIAB | |||
|---|---|---|---|---|
| Variable | Men n = 167 | Women* n = 345 | Men n = 1391 | Women* n = 1432 |
| Mean ± SD | ||||
| Age (yrs) | 43.2 ± 8.7 | 44.5 ± 8.9 | 50.9 ± 8.5 | 50.3 ± 8.4 |
| BMI (kg/m2) | 28.8 ± 5.6 | 29.7 ± 7.7 | 28.0 ± 4.5 | 27.7 ± 6.0 |
| WHR | 0.98 ± 0.07 | 0.90 ± 0.10 | 0.94 ± 0.07 | 0.82 ± 0.06 |
| Waist (cm) | 99.9 ± 14.1 | 97.5 ± 17.1 | 98.2 ± 12.0 | 87.2 ± 13.8 |
| Systolic blood pressure (mmHg) | 124.5 ± 16.4 | 117.8 ± 16.8 | 124.1 ± 17.7 | 115.4 ± 17.7 |
| Diastolic blood pressure (mmHg) | 79.5 ± 10.3 | 75.5 ± 9.3 | 73.3 ± 9.1 | 66.0 ± 9.7 |
| Total cholesterol (mmol/L) | 5.40 ± 1.33 | 5.17 ± 0.94 | 5.19 ± 0.94 | 5.25 ± 0.97 |
| HDL (mmol/L) | 1.02 ± 0.32 | 1.17 ± 0.33 | 1.25 ± 0.31 | 1.56 ± 0.39 |
| Geometric mean(95%CI) | ||||
| Fasting glucose (mmol/L) | 6.04(5.77-6.32) | 5.85(5.67-6.04) | 5.48(5.44-5.52) | 5.23(5.19-5.27) |
| CRP (mg/L) | 3.43(2.68-3.63) | 4.65(4.10-5.27) | 1.94(1.84-2.04) | 2.16(2.03-2.29) |
| Triglycerides (mmol/L) | 2.13(1.93-2.35) | 1.58(1.49-1.67) | 1.43(1.39-1.47) | 1.10(1.07-1.13) |
| Fibrinogen | 3.69(3.51-3.89) | 3.82(3.68-3.97) | 2.70(2.67-2.74) | 2.86(2.82-2.89) |
| Fasting Insulin (mU/L)** | 9.11(8.16-10.18) | 10.41(9.54-11.37) | 7.56(7.31-7.83) | 6.94(6.72-7.18) |
| HOMA-IR** | 2.45(2.15-2.78) | 2.71(2.45-3.00) | 1.84(1.77-1.91) | 1.61(1.55-1.67) |
| Percentages | ||||
| Glucose tolerance | ||||
| Diabetes | 23.3 | 25.2 | 6.8 | 5.4 |
| IFG/IGT | 19.8 | 16.5 | 12.8 | 9.5 |
| Normal | 56.9 | 58.3 | 80.4 | 85.1 |
| Smoking status | ||||
| Current | 45.5 | 42.9 | 13.0 | 8.9 |
| Former | 28.1 | 22.0 | 33.9 | 27.6 |
| Never | 21.0 | 27.2 | 49.4 | 59.6 |
*Women who are pregnant, using HRT or oral contraceptives are excluded.
**People with known diabetes on insulin (AusDiab), or insulin/tablets (DRUID) are excluded from these estimates.