TABLE 2.
Response and Remission Rates for Older Adults With Major Depression and Executive Dysfunction Receiving Problem-Solving Therapy or Supportive Therapya
| Outcome Measure and Assessment Week | Problem-Solving Therapy Group (N=110) |
Supportive Therapy Group (N=111) |
Odds Ratio | 95% CI | χ2 | df | p | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Completed Assessment (N) | N | % | Completed Assessment (N) | N | % | ||||||
| Responded | |||||||||||
| 3 | 101 | 10 | 9.9 | 104 | 14 | 13.5 | 0.71 | 0.27–1.81 | 0.6 | 1 | 0.428 |
| 6 | 94 | 28 | 29.8 | 95 | 21 | 22.1 | 1.49 | 0.74–3.04 | 1.5 | 1 | 0.228 |
| 9 | 87 | 41 | 47.1 | 92 | 27 | 29.3 | 2.14 | 1.11–4.17 | 6.0 | 1 | 0.014 |
| 12 | 90 | 51 | 56.7 | 97 | 33 | 34.0 | 2.54 | 1.35–4.79 | 9.7 | 1 | 0.002 |
| Remitted | |||||||||||
| 3 | 101 | 9 | 8.9 | 104 | 9 | 8.7 | 1.03 | 0.35–3.08 | 0.0 | 1 | 0.948 |
| 6 | 94 | 20 | 21.3 | 95 | 16 | 16.8 | 1.33 | 0.60–2.98 | 0.6 | 1 | 0.437 |
| 9 | 87 | 33 | 37.9 | 92 | 20 | 21.7 | 2.20 | 1.09–4.50 | 5.6 | 1 | 0.017 |
| 12 | 90 | 41 | 45.6 | 97 | 27 | 27.8 | 2.17 | 1.13–4.18 | 6.3 | 1 | 0.012 |
a
Response and remission rates were calculated on the basis of those who completed assessments. Response was defined as a reduction of ≥ 50% in Hamilton Depression Rating Scale (HAM-D) score since baseline, and remission was defined as a HAM-D score <10.