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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Inflamm Bowel Dis. 2010 Sep 1;17(1):260–267. doi: 10.1002/ibd.21443

Figure 1. MMP7 cleaves recombinant galectin-3.

Figure 1

Recombinant MMP7 and galectin-3 were incubated together for various time points. Reaction products were separated on SDS-PAGE, transferred to PVDF membranes and proteins detected by Coommassie Brilliant Blue staining. A. A 4 hr reaction mixture revealed three possible galectin-3 cleavage products (Bands A, B and C). B. A time course revealed galectin-3 cleavage within 5 minutes with the early appearance of Bands B and C. Band A became the predominant MMP7-induced galectin-3 cleavage product at the 24 hr incubation time point.