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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Exp Gerontol. 2010 Oct 15;46(1):65–72. doi: 10.1016/j.exger.2010.10.004

Figure 6. Physical performance measures.

Figure 6

Changes in (A) maximum grip strength and (B) time spent on rotarod. Other details as in Figure 2. Note decreases in grip strength during fentanyl administration although this decrease does not persist after 25 days of withdrawal. a p < 0.05 compared with 12-month old animals, b p < 0.05 compared with all other ages, c p < 0.05 compared with 18-month old animals. For rotarod performance, there were decreases in time with increasing age regardless of drug treatment. a p < 0.05 compared with 12-month old animals, b p < 0.05 compared with all other ages, c p < 0.05 compared with 18-month old animals.