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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Ther Drug Monit. 2010 Dec;32(6):741–748. doi: 10.1097/FTD.0b013e3181fa3c68

Figure 4.

Figure 4

Effect of clearing conditions on residual VCR concentration. Following the dosing of VCR, the catheter fragment was flushed with (A) varying volumes of normal saline; (B) normal saline with varying pH values; (C) normal saline followed by a second flush of varying compositions; (D) normal saline preceded by varying drug contact time in the catheter lumen. (E) 3 mL 0.9% normal saline flush followed by 5 or 10 mL of blood draw return cycles. Results are plotted as means or means ± SD from 2 or 3 independent experiments, respectively.