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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Ther Drug Monit. 2010 Dec;32(6):741–748. doi: 10.1097/FTD.0b013e3181fa3c68

Table 1.

Catheter clearing procedure

Catheter Clearing
  1. Fit a sterile 3-way stopcock with a sterile 3 mL sample syringe (syringe #1) and 5 mL waste syringe (syringe #2), primed with normal saline

  2. Connect the apparatus to the catheter via a needless hub aseptically; the catheter valves should be set to the “off” position

  3. Connect a sterile 5 mL syringe (syringe #3) to the third and inline end of the 3-way stopcock for normal saline flush. Syringe should be pre-filled with 5 mL normal saline

  4. Open the distal stopcock value to syringe #2

  5. Draw back mL of blood and then return to the patient over 3-5 seconds. Repeat 4 times. Do not return blood if there is any resistance or clots noted in the syringe.

  6. Close the stopcock valve on syringe #2 and open the valve to syringe #3

  7. Infuse 2 mL of normal saline through syringe #3

  8. Close stopcock valve on syringe #3 and open the valve to syringe #2

  9. Draw back 5 mL of blood and hold in syringe #2

  10. Close stopcock valve on syringe #2 and open the valve to syringe #1

  11. Draw 2.5 mL of blood into syringe #1 as the final sample

  12. Close stopcock valve on syringe #1 and open the valve to syringe #2

  13. Return the blood in syringe #2 back to the patient

  14. Close stopcock valve on syringe #2 and open the valve to syringe #3

  15. Infuse the remaining 3 mL of normal saline through syringe #3

  16. Remove syringe #1 and transfer blood sample into a green top (sodium heparin) blood collection tube

Catheter clearing procedure for double lumen catheters
Samples may be obtained from either the dosing or the non-dosing lumen. In both cases, the above clearing procedure for a single catheter should be followed.