Figure 2.
Images of BChE−/− mice injected IM or IV with cross-linked huBChE*/PLL-g-PEO complexes, Z+/− = 2, 40% degree of cross-linking. The fluorescence was from BChE labeled with IRDye 800CW. A) Pre-dosing and B) 2 hours post IM injection; C) Pre-dosing and D) 2 hours post IV injection into the tail vein. Images of the brain tissues at 24 h after E) IM treatment with huBChE*/PLL-g-PEO complexes; F) IV treatment with huBChE*/PLL-g-PEO complexes; G) IM treatment with free huBChE*.
