Figure 4.

BChE activity in mouse brain supernatants: (A) at 23h post IM injection of free hrBChE into BChE−/− mice (1, 2); hrBChE/PLL-g-PEO complex, Z+/−=7 (3–5); (B) at 23h post IV injection of hrBChE/PLL-g-PEO complex, Z+/−=7 into wild-type mice (1–3); and control wild type mouse brain (4). Human plasma (lane marked HS) was used as a control with T representing the tetramer, D the dimer, and M the monomer forms of BChE.