Table 1.
The effect of PPC on heart function
| Pre-ischaemic | Reperfused | |||||
|---|---|---|---|---|---|---|
| Control | Diazoxide | Nifedipine | Control | Diazoxide | Nifedipine | |
| n | 8 | 10 | 9 | 3 | 3 | 3 |
| LVEDP (mmHg) | 2.1 ± 0.6 | 3.9 ± 1.2 | 3.5 ± 6.0 | 52.5 ± 12.6* | 25.5 ± 11.5* | 24.1 ± 12.2 |
| LVDP (mmHg) | 96.6 ± 3.4 | 88.5 ± 5.3 | 78.7 ± 4.5# | 14.9 ± 5.6* | 61.2 ± 4.6* | 57.2 ± 4.9 |
| dP/dtmax (mmHg·s−1) | 2477 ± 127 | 2467 ± 132 | 1805 ± 67# | 454 ± 174* | 1720 ± 357* | 1494 ± 100 |
| dP/dtmin (mmHg·s−1) | 1532 ± 89 | 1531 ± 81 | 1305 ± 64 | 384 ± 124* | 1164 ± 182 | 1131 ± 97 |
| LDH (%) | 100 | 33 ± 8.0# | 46 ± 10.0# | |||
#
P < 0.05 vs. control.
*
P < 0.05 vs. pre-ischaemic baseline.