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Effect of curcumin on compound 48/80-induced histamine release from rat peritoneal mast cell (RPMC). RPMCs were preincubated with curcumin at 37℃ for 5 minutes prior to the incubation with compound 48/80. Curcumin dose-dependently inhibited compound 48/80-induced histamine release. Each data value represents the mean±S.E.M. of five independent experiments. *P<0.001, significantly different from the control value. C48/80: compound 48/80.
