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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: J Immunol. 2010 Oct 13;185(10):5953–5961. doi: 10.4049/jimmunol.1001628

Figure 4. 3-HAA inhibits EAE when treatment begins before or at early disease onset but is not effective when treatment begins at the peak of EAE.

Figure 4

EAE was induced in C57BL/6 mice as described in Fig. 2. Tested mice were injected i.p. with 200 mg/kg of 3-HAA daily, beginning on day 12 (A), day 16 (B), or day 20 (C) p.i. until the end of the experiment. Control mice received the same amount of PBS. Arrows indicate the start date of the treatment. Data are presented as mean ± SE of clinical scores (n = 5). One representative of two independent experiments is shown.