Table 1.
Gene/variant | Reference SNP | Location | Sequence [SNP] | Expected allele frequencies |
---|---|---|---|---|
Cytochrome P450 2D6/CYP2D6*4 | rs3892097 | 22q13.1 | CCCCTTACCCGCATCTCCCACCCCCA [A/G] GACGCCCCTTTCGCCCCAACGGTCT |
A: 0.763 G: 0.237a |
UDP-glucuronosyltransferase 2B15/UGT2B15*2 | rs1902023 | 4q13 | TTTATCCTACATCTTTAACTAAAAAT [G/T] ATTTGGAAGATTCTCTTCTGAAAAT |
G: 0.560 T: 0.440b |
UDP-glucuronosyltransferase 1A8/UGT1A8*2 | rs1042597 | 2q37 | CTCTGTGGTCTTCGCCAGGAATAG [C/G] TTGCCACTATCTTGAAGAAGGTGCA |
C: 0.714 G: 0.286a |
Notes: Allele frequencies reported for Caucasians on NCBI dbSNP database: http://www.ncbi.nlm.nih.gov/snp;
Allele frequencies reported for Europeans on ALFRED database: http://alfred.med.yale.edu21.
Abbreviation: SNP, single nucleotide polymorphism.