Table 3.
Univariate analysis of predictive factors for combined major-vessel resection
| Variables | Conventional (n = 346) | Combined (n = 25) | P value | |
| n (%) | n (%) | |||
| Patient-related | ||||
| Age (yr) | ≤ 64 | 179 (52) | 14 (56) | 0.84 |
| ≥ 65 | 167 (48) | 11 (44) | ||
| Gender | Male | 209 (60) | 14 (56) | 0.68 |
| Female | 137 (40) | 11 (44) | ||
| Primary-related | ||||
| Site | Colon | 204 (59) | 19 (76) | 0.14 |
| Rectum | 142 (41) | 6 (24) | ||
| Histology | Moderate | 223 (64) | 14 (56) | 0.40 |
| Others | 123 (36) | 11 (44) | ||
| Dukes stage | A/B | 120 (35) | 4 (16) | 0.08 |
| C | 226 (65) | 21 (84) | ||
| Liver-related | ||||
| Hepatectomy | Initial | 296 (86) | 16 (64) | < 0.01 |
| Repeat | 50 (14) | 9 (36) | ||
| Distribution | Unilobar | 213 (62) | 12 (48) | 0.21 |
| Bilobar | 133 (38) | 13 (52) | ||
| Number | ≤ 2 | 222 (64) | 14 (56) | 0.52 |
| ≥ 3 | 124 (36) | 11 (44) | ||
| Maximum tumor size (mm) | ≤ 30 | 197 (57) | 6 (24) | < 0.01 |
| > 30 | 149 (43) | 19 (76) | ||
| Prehepatectomy CEA (ng/mL) | < 10 | 175 (54) | 17 (68) | 0.21 |
| ≥ 10 | 150 (46) | 8 (32) | ||
| Treatment-related | ||||
| Extent of hepatectomy | Major | 112 (32) | 13 (52) | 0.05 |
| Minor | 234 (68) | 12 (48) | ||
| PVE | Performed | 44 (13) | 7 (28) | 0.06 |
| Not performed | 302 (87) | 18 (72) | ||
| Staged procedure | Performed | 20 (6) | 1 (4) | > 0.99 |
| Not performed | 326 (94) | 24 (96) | ||
| Hepatectomy with ablation | Performed | 26 (8) | 4 (16) | 0.13 |
| Not performed | 320 (92) | 21 (84) | ||
| Prehepatectomy chemotherapy | Performed | 63 (18) | 11 (44) | < 0.01 |
| Not performed | 283 (82) | 14 (56) |
Moderate: Moderately differentiated adenocarcinoma; CEA: Carcinoembryonic antigen; PVE: Portal vein embolization.