. Author manuscript; available in PMC: 2011 Dec 1.

Published in final edited form as: Bioorg Med Chem. 2010 Oct 28;18(23):8264–8269. doi: 10.1016/j.bmc.2010.10.010

Table 3.

Antibacterial and antifungal activities of 19-O-β-d-glucopyranosyl-19-hydroxy-cholest-4-en-3-one (1) and 19-O-β-d-N-acetyl-2-aminoglucopyranosyl-19-hydroxy-cholest-4-en-3-one (2).

	antibacterial activity (µg/mL)		antifungal activity (µg/mL)^a

cmpd.	MRSA MIC	VREF MIC	MIC
1	6.3	6.3	25
2	3.1	12.5	25

Using amphotericin-resistant Candida albicans. MRSA=methicillin-resistant Staphylococcus aureus; VREF=vancomycin-resistant Enterococcus faecium.