Table 2.
Urinary nicotine metabolite profile in 104 smokers.
| % of Total-NIC-Eqa |
Creatinine-adjusted levels (nmol/mg creatinine)b |
|||
|---|---|---|---|---|
| Mean ± S.D. (95% CI)c | Range | Mean ± S.D. (95% CI) | Range | |
| 3HC | 33.6 ± 8.7 (32.0–35.4) | 5.9–53.4 | 42.4 ± 25.2 (37.6–47.3) | 0.78–145 |
| 3HC-Gluc | 16.7 ± 7.8 (15.1–18.2) | 3.3–43.6 | 21.8 ± 18.5 (18.2–25.3) | 0.44–124 |
| Cotinine | 11.0 ± 6.6 (9.8–12.2) | 2.9–32.0 | 14.2 ± 11.9 (11.9–16.5) | 0.97–70 |
| Nicotine | 10.6 ± 7.3 (9.2–12.0) | 0.58–31.7 | 12.9 ± 11.5 (11.0–15.2) | 0.42–64 |
| 4HPBA | 8.9 ± 3.7 (8.1–9.6) | 3.1–32.3 | 10.6 ± 6.0 (9.4–11.8) | 0.95–37 |
| Cotinine-Gluc | 7.3 ± 3.4 (6.6–8.0) | 0–18.8 | 8.7 ± 5.3 (7.6–9.7) | 0.00–26 |
| Nicotine-N′-Oxide | 4.8 ± 2.5 (4.3–5.3) | 1.4–13.4 | 5.6 ± 3.2 (4.9–6.2) | 0.36–18 |
| Nicotine-Gluc | 4.3 ± 3.4 (3.6–4.9) | 0–19.5 | 5.0 ± 4.6 (4.2–5.8) | 0.00–31 |
| Cotinine-N-Oxide | 2.8 ± 0.77 (2.7–3.0) | 1.2–5.0 | 3.4 ± 1.6 (7.6–9.7) | 0.58–8.1 |
a
Ratio of individual nicotine metabolite (μM) measured as a percentage of total urinary nicotine metabolites [Total-NIC-Eq (μM)].
b
Ratio of individual nicotine metabolite (μM) measured as a percentage of urinary creatinine (mg).
c
S.D. = standard deviation; CI = confidence interval.