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DTH reaction in E-selectin-tolerized compared with PBS-tolerized SHR-SP rats. Ear thickness determination was as described in Materials and Methods; rat treatment consisted of tolerization to PBS or E-selectin (E) after immunization and sensitization with E. An unpaired t test revealed a significant difference between the two groups (n = 3; *, P < 0.05). Data are presented as mean ± SEM.
