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. 2010 Feb 15;2(2):109–116. doi: 10.4251/wjgo.v2.i2.109

Table 1.

Major series on IPHC and/or EPIC after cytoreductive surgery for PMP, DMPM, and CRPC

Chief investigator Year Treatment center Type n Intraperitoneal chemotherapy Survival (%)
3-yr 5-yr
Piso et al[1] 2001 Hanover, Germany PMP 17 IPHC: cisplatin 75 -
Butterworth et al[2] 2002 Vancouver, Canada PMP 11 EPIC: 5-FU + mitomycin 60 -
Witkamp et al[3] 2001 Amsterdam, Netherlands PMP 46 IPHC: mitomycin 81 -
Sugarbaker et al[4] 2001 Washington, USA PMP 501 EPIC: 5-FU + mitomycin - 80
IPHC: mitomycin
Loggie et al[5] 2001 Winston-Salem, USA DMPM 12 IPHC: mitomycin 50 -
Sebbag et al[6] 2000 Washington, USA DMPM 33 IPHC: cisplatin + doxorubicin 56 47
Sugarbaker et al[7] 2003 Washington, USA DMPM 68 IPHC: cisplatin + doxorubicin 60 50
EPIC: paclitaxel
Feldman et al[8] 2003 Bethesda, USA DMPM 49 IPHC: cisplatin ± paclitaxel - 59
Fujimura et al[9] 1999 Kanazawa, Japan CRPC 14 IPHC: cisplatin + mitomycin + etoposide 21 -
Witkamp et al[10] 2001 Amsterdam, Netherlands CRPC 29 IPHC: mitomycin 23 -
Elias et al[11] 2001 Villejuif, France CRPC 64 IPHC: mitomycin ± cisplatin 47 27
EPIC: mitomycin + 5-FU
Pestieau et al[12] 2000 Washington, USA CRPC 104 IPHC: mitomycin 45 30
EPIC: 5-FU
Zoetmulder et al[13] 2002 Amsterdam, Netherlands CRPC 94 IPHC: mitomycin - 30
Shen et al[14] 2004 Winston-Salem, USA CRPC 77 IPHC: mitomycin 25 17
Glehen et al[15] 2004 Multi-institutions CRPC 506 IPHC or EPIC - -

IPHC: Intraperitoneal hyperthermic chemotherapy; EPIC: Early postoperative intraperitoneal chemotherapy; PMP: Pseudo-myxoma peritonei; DMPM: Diffuse malignant peritoneal mesothelioma; CRPC: Colo-rectal peritoneal carcinomatosis.