Table 1. Mean blood counts and weight of control vs. rapamycin-treated mice over time.
| Day 0
|
Day 7
|
Days 14-21
|
Death
|
|||||
|---|---|---|---|---|---|---|---|---|
| Measurement | Control | Treated | Control | Treated | Control | Treated | Control | Treated |
| WBC, × 103 Cells per μl | 48.2 (4.7–200) | 43.1 (2.3–408) | 63.3 (2.2–328) | 18.1 (2.9–200) | 60 (8.3–138) | 15.3 (4.0–65.3) | 67 (8.3–328) | 32.5 (2.5–164) |
| Hgb, g/dl | 12.7 (9.8–16.5) | 12.3 (8.7–15.9) | 11.8 (7.2–17.1) | 12.3 (7.3–15.8) | 10.8 (8.5–12.7) | 12.3 (7.6–16.1) | 10.7 (6.5–15.5) | 12.4 (8.4–16.6) |
| Plt, × 103 Cells per μl | 631 (219–1,203) | 666 (229–1,344) | 652 (156–1,600) | 556 (212–1,663) | 483 (137–795) | 563 (171–881) | 488 (135–768) | 584 (147–1,018) |
| Weight (g) | 29.1 ± 3.4 | 29.14 ± 5.1 | 29.5 ± 3.4 | 28.9 ± 4.3 | 30.1 ± 5.1 | 29.3 ± 3.6 | 29.9 ± 4.5 | 29.4 ± 4.6 |
Ranges of values are given in parentheses. Normal ranges in mice (determined by Cell Technologies and based on ref. 73) are as follows: WBC, 1.8–10.7; Hgb, 11.0–15.1; Plt, 592–972. Weight is given as mean ± SD. Hgb, hemoglobin content; Plt, platelet count.