Figure 4.

Histogram shows the difference in infarct size prior to intramyocardial gene delivery at 3 d and 8 wk after infarction in control animals (left block) and animals treated with hepatocyte growth factor gene (VM202) (right block) measured on DE-MR imaging (black and white bars) and postmortem (gray bars). Note the decline in infarct size was greater in gene treated animals compared with control animals. ^aP < 0.05 compared with 3 d acute infarction. ^cP < 0.05 compared with 8 wk chronic infarction in control animals. %LV: Percentage of LV mass[59].