Table 2.
The core genome components in six Plasmodium species involved in fundamental cellular processes.
| Function description | Examples of GO classes | Orthologous families |
|---|---|---|
| Replication | GO:0003688 (DNA replication origin binding) | ORTHOMCL1162 |
| ORTHOMCL2123 | ||
| GO:0003887 (DNA-directed DNA polymerase activity) | ORTHOMCL2751 | |
| ORTHOMCL61 | ||
| ORTHOMCL2153 | ||
| ORTHOMCL593 | ||
| ORTHOMCL2507 | ||
| GO:0005663 (DNA replication factor C complex) | ORTHOMCL1738 | |
| ORTHOMCL1861 | ||
| ORTHOMCL443 | ||
| ORTHOMCL513 | ||
| ORTHOMCL1911 | ||
| ORTHOMCL2437 | ||
| ORTHOMCL3328 | ||
| GO:0005662 (DNA replication factor A complex) | ORTHOMCL683 | |
| Transcription | GO:0000122 (negative regulation of transcription from RNA polymerase II promoter) | ORTHOMCL190 |
| GO:0000126 (transcription factor TFIIIB complex) | ORTHOMCL2349 | |
| ORTHOMCL802 | ||
| GO :0016251 (general RNA polymerase II transcription factor activity) | ORTHOMCL2179 | |
| GO:0003702 (RNA polymerase II transcription factor activity) | ORTHOMCL1522 | |
| ORTHOMCL3420 | ||
| GO:0003712 (transcription cofactor activity) | ORTHOMCL3015 | |
| GO:0003700 (transcription factor activity) | ORTHOMCL1875 | |
| ORTHOMCL3398 | ||
| ORTHOMCL880 | ||
| ORTHOMCL2851 | ||
| ORTHOMCL2947 | ||
| Translation | GO:0006412 (translation) | ORTHOMCL1544 |
| ORTHOMCL3343 | ||
| ORTHOMCL1471 | ||
| ORTHOMCL1516 | ||
| ORTHOMCL1698 | ||
| ORTHOMCL2550 | ||
| ORTHOMCL1856 | ||
| GO:0003743 (translation initiation factor activity) | ORTHOMCL1832 | |
| ORTHOMCL1842 | ||
| ORTHOMCL2705 | ||
| ORTHOMCL3178 | ||
| ORTHOMCL2122 | ||
| ORTHOMCL940 | ||
| ORTHOMCL3423 | ||
| GO:0003746 (translation elongation factor activity) | ORTHOMCL350 | |
| ORTHOMCL1193 | ||
| ORTHOMCL2152 | ||
| ORTHOMCL2232 | ||
| ORTHOMCL1803 | ||
| ORTHOMCL516 | ||
| ORTHOMCL1744 | ||
| GO:0006449 (regulation of translational termination) | ORTHOMCL2253 | |
| Repair | GO:0006289 (nucleotide-excision repair) | ORTHOMCL444 |
| GO:0000724 (double-strand break repair via homologous recombination) | ORTHOMCL1863 | |
| GO:0006302 (double-strand break repair) | ORTHOMCL867 | |
| GO:0006281 (DNA repair) | ORTHOMCL543 | |
| ORTHOMCL1058 | ||
| Cell motion | GO:0007017 (microtubule-based process) | ORTHOMCL2981 |
| ORTHOMCL1078 | ||
| GO:0003777 (microtubule motor activity) | ORTHOMCL2241 | |
| ORTHOMCL2737 | ||
| GO:0007018 (microtubule-based movement) | ORTHOMCL1635 | |
| ORTHOMCL2737 | ||
| ORTHOMCL1944 | ||
| GO:0030048 (actin filament-based movement) | ORTHOMCL278 | |
| ORTHOMCL1146 | ||
| ORTHOMCL428 | ||