Table 3.
Steroid hormone levels in urine and serum
| Wild type | Hnf1a-null | Ratioa | P value | |
|---|---|---|---|---|
| Urine | ||||
| Aldosterone (ng/ml) | 2.76 ± 0.27 | 8.09 ± 1.18 | 2.93 | 0.0009 |
| Corticosterone (ng/ml) | 128.9 ± 12.18 | 575.1 ± 53.7 | 4.46 | <0.0001 |
| Serum | ||||
| Aldosterone (ng/ml) | 23.4 ± 4.19 | 43.8 ± 7.33 | 1.87 | 0.029 |
| Corticosterone (ng/ml) | 14.51 ± 2.48 | 72.21 ± 6.15 | 4.97 | <0.0001 |
| DHEA (ng/ml) | 1.31 ± 0.01 | 0.24 ± 0.13 | 0.18 | 0.015 |
| DHEAS (ng/ml) | 19.0 ± 3.47 | 5.25 ± 0.88 | 0.28 | 0.0018 |
| Progesterone (ng/ml) | 229 ± 18.8 | 663 ± 208 | 2.90 | 0.0325 |
a
Ratio of Hnf1a-null value to wild-type value.