Effects of various progestins on serum starvation-induced cell death and apoptosis in G/T cell cultures. All data represent means ± sem. A, Changes in G/T cell serum starvation-induced death measured by trypan blue exclusion after 8 d of treatment with 1 and 10 nm 20β-S. *, P < 0.001; **, P < 0.0001 compared with vehicle control (CTL) by ANOVA and Dunnett’s multiple comparison test, n = 9. B, Changes in cell death after 7 d of treatment with various concentrations of 20β-S, Org OD 02-0, or R5020. *, P < 0.05, compared with vehicle control (Veh) by ANOVA and Dunnett’s multiple comparison test, n = 21. Org 02, Org OD 02-0. C, Percent TUNEL-stained nuclei after 7 d of treatment with various concentrations of 20β-S and R5020. *, P < 0.001, compared with vehicle control by ANOVA and Dunnett’s multiple comparison test, n = 20.