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. 2010 Oct 6;151(12):5807–5817. doi: 10.1210/en.2010-0783

Figure 1.

Figure 1

Development of the Kiss1 sex difference in the AVPV/PeN of mice. A, Representative photomicrographs of ISH for Kiss1 mRNA in the AVPV/PeN of male (M) and female (F) mice on PND 6, 10, and 14. B, Mean number of Kiss1 neurons in the AVPV/PeN of females and males over the course of early postnatal development. Kiss1 cells were first detected in each sex on PND 10. The number of Kiss1 neurons was significantly higher in females than males on PND 12 and later. C, Mean level of Kiss1 mRNA/cell in the AVPV/PeN of females and males over the course of early postnatal development. This measure was not significantly higher in females than males until PND 16. *, Significantly different from males of same age.