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. Author manuscript; available in PMC: 2010 Dec 8.
Published in final edited form as: Kidney Int. 2009 Jan 7;75(6):617–625. doi: 10.1038/ki.2008.646

Figure 6. Effect of bisphosphonates on calcification of rat aortas in culture.

Figure 6

Top: Aortas were incubated in DMEM containing 3.8 mM phosphate, 3.75 U/ml of alkaline phosphatase, 25 μM warfarin, and the indicated concentrations of bisphosphonate for 9 days. Results are the means±s.e. of seven aortic rings. Bottom: Injured and uninjured aortas were incubated in DMEM with 3.8 mM phosphate, with or without 3.75 U/ml of alkaline phosphatase, and the indicated concentrations of pamidronate for 9 days. Results are the means±s.e. of at least three aortic rings.