Table 2.
LMS-QoL values and changes from baseline.
| Time points and periods | Parameters | Total group | Treatment-naive group |
Pre-treated group |
|---|---|---|---|---|
| Baseline (B) | Mean (SD) | 19.51 (4.19) | 19.54 (4.26) | 19.47 (4.12) |
| Median | 19.00 | 20.00 | 19.00 | |
| 95% CI (mean) | 18.92; 20.10 | 18.72; 20.36 | 18.61; 20.33 | |
| Month 6 (M6) | Mean (SD) | 20.95 (4.63) | 21.35 (4.63) | 20.48 (4.61) |
| Median | 21.00 | 22.00 | 21.00 | |
| 95% CI (mean) | 20.26; 21.65 | 20.40; 22.31 | 19.45; 21.51 | |
| Month 12 (M12) | Mean (SD) | 20.94 (4.69) | 21.73 (4.76) | 19.98 (4.43) |
| Median | 21.00 | 21.50 | 20.00 | |
| 95% CI (mean) | 20.25; 21.63 | 20.78; 22.69 | 19.00; 20.96 | |
| Change B to M6 | Mean (SD) | 1.41 (3.97)* | 1.90 (4.08)* | 0.82 (3.77) |
| Median | 1.00 | 1.00 | 1.00 | |
| 95% CI (mean) | 0.81; 2.00 | 1.06; 2.74 | -0.02; 1.67 | |
| Change B to M12 | Mean (SD) | 1.33 (4.24)* | 2.10 (4.56)* | 0.40 (3.64) |
| Median | 1.00 | 1.00 | 1.00 | |
| 95% CI (mean) | 0.70; 1.96 | 1.19; 3.02 | -0.41; 1.20 |
SD, standard deviation; CI, confidence interval; *, p < 0.001. Differences between groups were not statistically tested.