Table 4.
FIS values and differences from baseline.
| Time points and periods | Parameters | Total Group | Treatment-naive group | Pre-treated group |
|---|---|---|---|---|
| Baseline (B) | Mean (SD) | 60.53 (34.24) | 56.25 (32.65) | 65.51 (35.54) |
| Median | 59.00 | 55.00 | 70.00 | |
| 95% CI (mean) | 55.72; 65.34 | 49.97; 62.54 | 58.10; 72.91 | |
| Month 6 (M6) | Mean (SD) | 51.15 (35.35) | 45.68 (33.33) | 57.79 (36.76) |
| Median | 44.50 | 40.00 | 50.00 | |
| 95% CI (mean) | 45.83; 56.47 | 38.81; 52.54 | 49.36; 65.83 | |
| Month 12 (M12) | Mean (SD) | 54.07 (35.18) | 47.97 (33.78) | 61.46 (35.62) |
| Median | 49.00 | 43.50 | 63.00 | |
| 95% CI (mean) | 48.88; 59.26 | 41.20; 54.74 | 53.58; 69.33 | |
| Change B to M6 | Mean (SD) | -9.17 (27.08)*** | -11.33 (27.67)*** | -6.62 (26.32)* |
| Median | -6.00 | -7.00 | -3.00 | |
| 95% CI (mean) | -13.24; -5.09 | -17.03; -5.64 | -12.51; -0.73 | |
| Change B to M12 | Mean (SD) | -6.04 (29.04)** | -8.50 (29.35)** | -3.06 (28.57) |
| Median | -5.00 | -8.00 | -3.00 | |
| 95% CI (mean) | -10.32; -1.76 | -14.38; -2.62 | -9.38; 3.25 |
SD, standard deviation; CI, confidence interval; ***, p < 0.001; **, p < 0.01; *, p < 0.05. Differences between groups were not statistically tested.