Table 1.

Assessment of CFA Effects on Mouse Behavior Using a Functional Observation Battery. Locomotor Activity (Grid Cross), Exploration in the Open Field (Number of Rears), the Preyer Reflex, Animal Weight and Transfer Arousal were Quantitatively Assessed Over a Time Course of 6 Weeks After CFA or Saline Injection. There were no Significant Differences Between Groups at Any Time Point. n=6 Per Condition

Activity - # Grid Crosses
Week	Saline			CFA
	Mean		SE	Mean		SE
Pre	14.6	±	4.4	11.4	±	4.3
1 wk	16.2	±	2.0	17.8	±	3.5
4 wk	16.1	±	5.4	17.4	±	4.3
6 wk	17.6	±	2.8	15.8	±	1.2
Exploration - # Rears
Week	Saline			CFA
	Mean		SE	Mean		SE
Pre	1.8	±	0.6	1.6	±	0.7
1 wk	0.8	±	0.3	1.5	±	0.9
4 wk	1.9	±	0.9	1.4	±	0.7
6 wk	1.4	±	0.6	0.8	±	0.9
Preyer Reflex
Week	Saline			CFA
	Mean		SE	Mean		SE
Pre	1.9	±	0.1	1.7	±	0.2
1 wk	1.8	±	0.2	2	±	0
4 wk	1.6	±	0.2	1.8	±	0.2
6 wk	1.8	±	0.2	2	±	0
Weight (g)
Week	Saline			CFA
	Mean		SE	Mean		SE
Pre	22.9	±	0.3	23.2	±	0.4
1 wk	22.9	±	0.2	22.7	±	0.3
4 wk	24.8	±	0.1	25.3	±	0.3
6 wk	25.9	±	0.2	27	±	0.6
Transfer Arousal (Sec)
Week	Saline			CFA
	Mean		SE	Mean		SE
Pre	17.6	±	2.9	19.0	±	6.6
1 wk	11.8	±	2.4	11.3	±	3.1
4 wk	8.4	±	2.9	8.2	±	2.8
6 wk	3.8	±	0.2	4.0	±	0.8