Fig. 1.

Change in the indices of rheumatoid arthritis (RA) disease activity and in the variables used to calculate those indices over the 24-week study. The indices and variables shown are the 28-joint disease activity score using erythrocyte sedimentation rate (DAS28-ESR), the clinical and simplified disease activity indices (CDAI and SDAI, respectively), 28-joint swollen and tender joint counts (SJC28 and TJC28, respectively), visual analog scale (VAS) of patient and physician global assessment (PGA and MDGA, respectively), C-reactive protein (CRP) and ESR. The treatment received was either tocilizumab (TCZ) or methotrexate (MTX). Mean values and standard deviations are shown. The data of the TCZ group and control group are shown as mean values among the 53 TCZ patients and 37 MTX patients who completed the 24-week study