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. Author manuscript; available in PMC: 2010 Dec 9.
Published in final edited form as: Immunol Lett. 2009 Nov 4;128(1):29–35. doi: 10.1016/j.imlet.2009.10.005

Fig. 2.

Fig. 2

Cholera toxin. (A) Cholera toxin consists of the two main subunits, cholera toxin A subunit (CTA) and cholera toxin B subunit (CTB). CTB is accountable for the adjuvant capabilities, while CTA’s toxicity causes severe gastrointestinal symptoms. (B) Thus, during production of vaccines/adjuvants, CTA is cleaved off and CTB is linked to the antigen of choice. (C) CTB binds to the GM-1 receptor on enterocytes and enhances recognition of the linked antigen by the immune system.