TABLE II.

Key concepts and safety implications

Regulatory authorities might consider a re-evaluation of currently applied safety tests for novel (eg, genetically modified) food compounds.

Patients should be advised that threshold levels might vary in situations of altered protein digestion. This problem also affects current efforts to define no-observed-adverse-effect levels for food allergens.

Dietary recommendations and repeated allergologic testing of long-term acid-suppressed patients could prevent unexpected allergic reactions on food ingestion.