Fig. 5.
Positive reactions in intradermal skin tests underline the biological relevance of the humoral and cellular allergic response towards a food allergen when combined with anti-acid substances. The most intensive reactions to codfish were found in the groups treated with codfish together with either base powder, Rennie® Antacidum or Rennie® Digestif. Positive controls were performed with compound 48/80, and negative controls (data not shown) with phosphate-buffered saline and the control allergen hazelnut extract. Skin reactivity indexes were calculated as the diameter of skin reactivity×densitometrical signal intensity×number of reactive mice/number of tested mice.
