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. Author manuscript; available in PMC: 2010 Dec 9.
Published in final edited form as: Immunol Lett. 2008 Dec 25;122(1):68–75. doi: 10.1016/j.imlet.2008.12.002

Fig. 3.

Fig. 3

Phl p 5-specific IgG antibody responses after i.d. and gene gun immunization. (A) i.d. immunization of DNA mimotope constructs pCMV-F1 and pCMV-F1/Tet induced significantly higher Phl p 5-specific IgG responses after the third immunization (day 22) compared to injection of negative control pCMV-mock. Immunization with pCMV-P5 served as positive control. (B) Gene gun immunization with both DNA mimotope constructs after the fourth immunization (day 73) revealed 10-fold higher IgG levels than i.d. administration.The induction of IgG was highly specific in comparison to treatment with pCMV-mock. *P < 0.05, **P < 0.01.