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. Author manuscript; available in PMC: 2010 Dec 9.
Published in final edited form as: Pharmacotherapy. 2010 Sep;30(9):872–878. doi: 10.1592/phco.30.9.872

Table 3.

Univariate and Stepwise Adjusted Analysis for Log Insulin AUC During Oral Glucose Tolerance Testing and Atenolol-Induced Change in Glucose

Dependent Variable Covariate Entered Estimate Standard Error p Value
OGTT log insulin AUC
    Unadjusted Atenolol AUCn −1.03 0.32 0.008a
    Adjusted for BMIb Atenolol AUCn −0.32 0.35 0.38
Fasting glucose change
    Unadjusted Atenolol AUCn 7.97 3.8 0.06a
    Adjusted for sexb Atenolol AUCn 12.14 3.1 0.0025

OGTT = oral glucose tolerance test; AUC = area under the concentration-time curve; AUCn = weight-normalized area under the concentration-time curve within one dosing interval.

a

Only 14 of the 15 patients who had complete data in all fields were included in the analysis.

b

No other covariates entered the model as significant after adjustment for BMI.