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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Cell Metab. 2010 Dec 1;12(6):633–642. doi: 10.1016/j.cmet.2010.11.008

Figure 7. Combined loss of skeletal muscle PGC-1α and β results in rapid depletion of muscle glycogen during exercise.

Figure 7

(A) Mean glycogen levels (+/− SEM) of GC muscle of sedentary 2–3 month old male mice of the indicated genotypes is shown on the left. The results of GC glycogen levels post-exercise are shown on the right. (B) Mean blood lactate levels (+/− SEM) at baseline (white bars) and following exhaustive exercise (black bars) for all 4 genotypes (n=5–10/group). (Run-to-exhaustion protocol described in text and “Experimental Procedures”). * p < 0.05 vs. αβ+/+; ‡ p < 0.05 vs. α−/−; # p < 0.05 vs. β−/−.