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CO2 laser injury triggers a time and injury dependent up-regulation in soluble prostaglandin E2 (PGE2) levels. Secretions were collected from the airways of sham-operated and laser-injured airways at 12 hours, 24 hours, 48 hours, and 72 hours postinjury. PGE2 levels were assayed and compared across the various groups. Statistical significance is indicated by * representing P < .05 compared to sham PGE2 values for the specific time point.
