Table 3. Frequencies of alleles and genotypes of IL23R polymorphisms in patients with Fuchs’ syndrome and controls.
| SNP | Genotype allele | FHC (n=138) | Controls (n=407) | χ2 | p value | pc | OR (95% CI) |
|---|---|---|---|---|---|---|---|
|
rs17375018 |
AA |
9(6.5%) |
38(9.3%) |
1..36 |
0.309 |
NS |
0.68 (0.32–1.44) |
| |
AG |
62(44.9%) |
192(47.2%) |
0.209 |
0.647 |
NS |
0.91(0.62–1.35) |
| |
GG |
67(48.6%) |
177(43.5%) |
1.068 |
0.301 |
NS |
1.23(0.83–1.81) |
| |
A |
80(28.9%) |
268(32.9%) |
1.471 |
0.225 |
NS |
0.83(0.62–1.12) |
| |
G |
196(71.1%) |
546(67.1%) |
1.471 |
0.225 |
NS |
1.20(0.89–1.62) |
|
rs7517847 |
TT |
52(37.7%) |
134(32.9%) |
1.038 |
0.308 |
NS |
1.23(0.82–1.84) |
| |
GT |
56(40.6%) |
198(48.7%) |
2.696 |
0.101 |
NS |
0.72(0.49–1.06) |
| |
GG |
30(21.7%) |
75(18.4%) |
0.727 |
0.394 |
NS |
1.23(0.76–1.98) |
| |
G |
116(42.0%) |
348(42.8%) |
0.044 |
0.834 |
NS |
0.97(0.74–1.28) |
| |
T |
160(58.0%) |
466(57.2%) |
0.044 |
0.834 |
NS |
1.03 (0.78–1.36) |
|
rs11209032 |
GG |
29(20.2%) |
111(27.3%) |
2.114 |
0.146 |
NS |
0.71(0.45–1.13) |
| |
AG |
64(47.2%) |
212(52.1%) |
1.345 |
0.246 |
NS |
0.80(0.54–1.17) |
| |
AA |
45(32.6%) |
84(20.6%) |
8.173 |
0.004 |
0.036 |
1.86(1.21–2.86) |
| |
A |
154(56.2%) |
380(46.7%) |
6.851 |
0.009 |
NS |
1.44(1.10–1.90) |
| G | 122(43.8%) | 434(53.3%) | 6.851 | 0.009 | NS | 0.69(0.53–0.91) |
In the Table, FHC=Fuchs heterochromic cyclitis; OR=odds ratio; NS=not significant. 95%CI=95% confidence interval; pc=corrected p.