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. 2010 Dec 9;5(12):e14263. doi: 10.1371/journal.pone.0014263

Figure 1. Effect of altered cardiac workload on heart weight and the expression of miR-145 and miR-21.

Figure 1

(A) Relative heart weights (heart weight to body weight ratio, HW/BW) of animals undergoing ascending aortic stenosis (AS, n = 7) and heterotopic heart transplantation (HTX, n = 7). *** P<0.001 versus Native (n = 7), ### P<0.001 versus Sham (n = 6), one-way ANOVA, followed by a Bonferroni posthoc test. (B) Representative Northern blot and (C) densitometric analysis of miR-145 and miR-21 expression in the different groups. ** P<0.01 versus Native; ## P<0.01 versus Sham, one-way ANOVA followed by Bonferroni posthoc test.